Germline mutations among Polish patients with acute myeloid leukemia

Germline mutations among Polish patients with acute myeloid leukemia

Abstract Background A small but important proportion of patients (4–10 %) with AML have germline mutations. They can cause the development of AML at an earlier age, confer a higher risk of relapse or predispose to secondary leukemias, including therapy-related leukemias. The analysis of germline mut...

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Bibliographic Details
Main Authors: Aneta Bąk, Katarzyna Skonieczka, Anna Jaśkowiec, Anna Junkiert-Czarnecka, Marta Heise, Maria Pilarska-Deltow, Stanisław Potoczek, Maria Czyżewska, Olga Haus
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Acute myeloid leukemia
AML
germline mutations
CEBPA
DDX41
ETV6
Online Access:https://doi.org/10.1186/s13053-021-00200-2

Internet

https://doi.org/10.1186/s13053-021-00200-2

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