Reactive Chlorine Species Reversibly Inhibit DnaB Protein Splicing in Mycobacteria

ABSTRACT Intervening proteins, or inteins, are mobile genetic elements that are translated within host polypeptides and removed at the protein level by splicing. In protein splicing, a self-mediated reaction removes the intein, leaving a peptide bond in place. While protein splicing can proceed in t...

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Bibliographic Details
Main Authors: Christopher W. Lennon, Daniel Wahl, J. R. Goetz, Joel Weinberger
Format: Article
Language:English
Published: American Society for Microbiology 2021-10-01
Series:Microbiology Spectrum
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/Spectrum.00301-21