Interplay between Endoplasmic Reticular Stress and Survivin in Colonic Epithelial Cells

Interplay between Endoplasmic Reticular Stress and Survivin in Colonic Epithelial Cells

Sustained endoplasmic reticular stress (ERS) is implicated in aggressive metastasis of cancer cells and increased tumor cell proliferation. Cancer cells activate the unfolded protein response (UPR), which aids in cellular survival and adaptation to harsh conditions. Inhibition of apoptosis, in contr...

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Bibliographic Details
Main Authors: Rohit Gundamaraju, Ravichandra Vemuri, Wai Chin Chong, Stephen Myers, Shaghayegh Norouzi, Madhur D. Shastri, Rajaraman Eri
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Cells
Subjects:
endoplasmic reticular stress
apoptosis
survivin
unfolded protein response
inhibition of apoptosis
proliferation
Winnie
LS174T
colon
colon cancer
4PBA
tunicmycin
Online Access:http://www.mdpi.com/2073-4409/7/10/171

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http://www.mdpi.com/2073-4409/7/10/171

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