Low-Pass Genome Sequencing-Based Detection of Paternity: Validation in Clinical Cytogenetics

Low-Pass Genome Sequencing-Based Detection of Paternity: Validation in Clinical Cytogenetics

Submission of a non-biological parent together with a proband for genetic diagnosis would cause a misattributed parentage (MP), possibly leading to misinterpretation of the pathogenicity of genomic variants. Therefore, a rapid and cost-effective paternity/maternity test is warranted before genetic t...

Full description

Bibliographic Details
Main Authors: Keying Li, Yilin Zhao, Matthew Hoi Kin Chau, Ye Cao, Tak Yeung Leung, Yvonne K. Kwok, Kwong Wai Choy, Zirui Dong
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Genes
Subjects:
paternity test
genome sequencing
prenatal testing
low-pass genome sequencing
single-nucleotide variants
Online Access:https://www.mdpi.com/2073-4425/14/7/1357

Internet

https://www.mdpi.com/2073-4425/14/7/1357

Similar Items