Fibroblast Growth Factor 2 Attenuates Renal Ischemia-Reperfusion Injury via Inhibition of Endoplasmic Reticulum Stress

Acute kidney injury (AKI) is a serious clinical disease that is mainly caused by renal ischemia-reperfusion (I/R) injury, sepsis, and nephrotoxic drugs. The pathologic mechanism of AKI is very complex and may involve oxidative stress, inflammatory response, autophagy, apoptosis, and endoplasmic reti...

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Bibliographic Details
Main Authors: Xiaohua Tan, Qianyu Tao, Guixiu Li, Lijun Xiang, Xiaomeng Zheng, Tianzhen Zhang, Cuijiao Wu, Dequan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00147/full