Early loss of glutathione ‐s‐ transferase (GST) activity during diverse forms of acute renal tubular injury

Early loss of glutathione ‐s‐ transferase (GST) activity during diverse forms of acute renal tubular injury

Abstract Glutathione‐S‐transferases (GSTs) are a diverse group of phase II detoxification enzymes which primarily evoke tissue protection via glutathione conjugation to xenobiotics and reactive oxygen species. Given their cytoprotective properties, potential changes in GST expression during AKI has...

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Bibliographic Details
Main Authors: Richard A. Zager, Ali C. M. Johnson
Format: Article
Language:English
Published: Wiley 2022-06-01
Series:Physiological Reports
Subjects:
acute kidney injury
GST inhibitors
GST isotypes
oxidant stress
Online Access:https://doi.org/10.14814/phy2.15352

Internet

https://doi.org/10.14814/phy2.15352

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