Mistletoe lectin inhibits growth of Myc‐amplified small‐cell lung cancer

Mistletoe lectin inhibits growth of Myc‐amplified small‐cell lung cancer

Abstract Background Small‐cell lung cancer (SCLC) is the deadliest form of lung cancer but lacks targeted therapies. Methods We studied the effect of the natural product mistletoe lectin (ML) in pre‐clinical models of SCLC, focusing on cell lines with amplification of the myc family oncogenes C‐myc...

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Bibliographic Details
Main Authors: Mohammad A. Shatat, Betsy Gauthier, Suzy Yoon, Eric Yuan, Peiying Yang, Goutham Narla, Afshin Dowlati, Richard T. Lee
Format: Article
Language:English
Published: Wiley 2023-04-01
Series:Cancer Medicine
Subjects:
mistletoe
MYC
natural products
small‐cell lung cancer
targeted therapy
Online Access:https://doi.org/10.1002/cam4.5558

Internet

https://doi.org/10.1002/cam4.5558

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