Chick chorioallantoic membrane (CAM) assay for the evaluation of the antitumor and antimetastatic activity of platinum-based drugs in association with the impact on the amino acid metabolism

Chick chorioallantoic membrane (CAM) assay for the evaluation of the antitumor and antimetastatic activity of platinum-based drugs in association with the impact on the amino acid metabolism

The combination of in ovo and ex ovo chorioallantoic membrane (CAM) assay provides an excellent platform which extends its relevance in studying carcinogenesis to the field of screening of anticancer activity of platinum nanoparticles (PtNPs) and further study of the amino acids’ fluctuations in liv...

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Bibliographic Details
Main Authors: Katerina Mitrevska, Miguel Angel Merlos Rodrigo, Natalia Cernei, Hana Michalkova, Zbynek Splichal, David Hynek, Ondrej Zitka, Zbynek Heger, Pavel Kopel, Vojtech Adam, Vedran Milosavljevic
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Materials Today Bio
Subjects:
Platinum nanoparticles
Cisplatin
CAM assay
Breast cancer
Amino acids metabolism
TCA cycle
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006423000303

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http://www.sciencedirect.com/science/article/pii/S2590006423000303

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