Effectiveness and safety of 3 and 5 day courses of artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in an area of emerging artemisinin resistance in Myanmar

Effectiveness and safety of 3 and 5 day courses of artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in an area of emerging artemisinin resistance in Myanmar

Abstract Background Artemisinin resistance in Plasmodium falciparum has emerged and spread in Southeast Asia. In areas where resistance is established longer courses of artemisinin-based combination therapy have improved cure rates. Methods The standard 3-day course of artemether–lumefantrine (AL) w...

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Bibliographic Details
Main Authors: Kyaw Myo Tun, Atthanee Jeeyapant, Aung Hpone Myint, Zwe Thiha Kyaw, Mehul Dhorda, Mavuto Mukaka, Phaik Yeong Cheah, Mallika Imwong, Thaung Hlaing, Thar Htun Kyaw, Elizabeth A. Ashley, Arjen Dondorp, Nicholas J. White, Nicholas P. J. Day, Frank Smithuis
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Malaria Journal
Subjects:
Plasmodium falciparum
Artemether–lumefantrine
Artemisinin resistance
kelch13 mutation
Myanmar
Online Access:http://link.springer.com/article/10.1186/s12936-018-2404-4

Internet

http://link.springer.com/article/10.1186/s12936-018-2404-4

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