Single-Cell Transcriptome Profiling Unravels Distinct Peripheral Blood Immune Cell Signatures of RRMS and MOG Antibody-Associated Disease

Single-Cell Transcriptome Profiling Unravels Distinct Peripheral Blood Immune Cell Signatures of RRMS and MOG Antibody-Associated Disease

Relapsing-remitting multiple sclerosis (RRMS) and myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) are inflammatory demyelinating diseases of the central nervous system (CNS). Due to the shared clinical manifestations, detection of disease-specific serum antibody of the...

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Bibliographic Details
Main Authors: Ju Liu, Xiaoyan Yang, Jiali Pan, Zhihua Wei, Peidong Liu, Min Chen, Hongbo Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Neurology
Subjects:
RRMS
MOGAD
peripheral blood
single-cell RNA sequencing
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.807646/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2021.807646/full

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