Galantamine slows down plaque formation and behavioral decline in the 5XFAD mouse model of Alzheimer's disease.

The plant alkaloid galantamine is an established symptomatic drug treatment for Alzheimer's disease (AD), providing temporary cognitive and global relief in human patients. In this study, the 5X Familial Alzheimer's Disease (5XFAD) mouse model was used to investigate the effect of chronic...

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Bibliographic Details
Main Authors: Soumee Bhattacharya, Christin Haertel, Alfred Maelicke, Dirk Montag
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089454&type=printable