Loss of Y in leukocytes as a risk factor for critical COVID-19 in men

Loss of Y in leukocytes as a risk factor for critical COVID-19 in men

Abstract Background The COVID-19 pandemic, which has a prominent social and economic impact worldwide, shows a largely unexplained male bias for the severity and mortality of the disease. Loss of chromosome Y (LOY) is a risk factor candidate in COVID-19 due to its prior association with many chronic...

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Main Authors: Bożena Bruhn-Olszewska, Hanna Davies, Daniil Sarkisyan, Ulana Juhas, Edyta Rychlicka-Buniowska, Magdalena Wójcik, Monika Horbacz, Marcin Jąkalski, Paweł Olszewski, Jakub O. Westholm, Agata Smialowska, Karol Wierzba, Åsa Torinsson Naluai, Niklas Jern, Lars-Magnus Andersson, Josef D. Järhult, Natalia Filipowicz, Eva Tiensuu Janson, Sten Rubertsson, Miklós Lipcsey, Magnus Gisslén, Michael Hultström, Robert Frithiof, Jan P. Dumanski
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Genome Medicine
Online Access:https://doi.org/10.1186/s13073-022-01144-5

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https://doi.org/10.1186/s13073-022-01144-5

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