Effective-component compatibility of Bufei Yishen formula III ameliorated COPD by improving airway epithelial cell senescence by promoting mitophagy via the NRF2/PINK1 pathway

Effective-component compatibility of Bufei Yishen formula III ameliorated COPD by improving airway epithelial cell senescence by promoting mitophagy via the NRF2/PINK1 pathway

Abstract Background Effective-component compatibility of Bufei Yishen formula III (ECC-BYF III) demonstrates positive effects on stable chronic obstructive pulmonary disease (COPD). Purpose To investigate the mechanisms of ECC-BYF III on COPD rats from the aspect of airway epithelial cell senescence...

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Bibliographic Details
Main Authors: Min-yan Li, Yan-qin Qin, Yan-ge Tian, Kang-chen Li, Brian G. Oliver, Xue-fang Liu, Peng Zhao, Jian-sheng Li
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Pulmonary Medicine
Subjects:
Chronic obstructive pulmonary disease
Effective-component compatibility of Bufei Yishen formula III
Airway epithelial cell senescence
Oxidative stress
Mitophagy
Online Access:https://doi.org/10.1186/s12890-022-02191-9

Internet

https://doi.org/10.1186/s12890-022-02191-9

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