Inhibition of growth of colorectal cancer patient-derived subcutaneous xenografts using combined Wnt signaling pathway inhibitor and 5‑fluorouracil

Inhibition of growth of colorectal cancer patient-derived subcutaneous xenografts using combined Wnt signaling pathway inhibitor and 5‑fluorouracil

Purpose of the study. Was to analyze antitumor efficacy of the XAV 939 Wnt signaling pathway inhibitor and its combination with 5 fluorouracil in subcutaneous xenografts derived from patients with colorectal cancer.Materials and methods. Antitumor efficacy of the agents and their combination was stu...

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Bibliographic Details
Main Authors: A. S. Goncharova, A. V. Galina, D. V. Khodakova, G. Yu. Egorov, A. Yu. Maksimov, E. N. Kolesnikov, E. F. Komarova, A. A. Kiblitskaya, E. V. Zaikina, L. Z. Kurbanova, M. V. Mindar
Format: Article
Language:Russian
Published: QUASAR, LLC 2022-03-01
Series:Исследования и практика в медицине
Subjects:
colorectal cancer
xenograft
murine models
in vivo studies
wnt signaling pathway
wnt inhibitor
Online Access:https://www.rpmj.ru/rpmj/article/view/746

Internet

https://www.rpmj.ru/rpmj/article/view/746

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