<i>Artemisia annua</i> L. Polyphenol-Induced Cell Death Is ROS-Independently Enhanced by Inhibition of JNK in HCT116 Colorectal Cancer Cells

<i>Artemisia annua</i> L. Polyphenol-Induced Cell Death Is ROS-Independently Enhanced by Inhibition of JNK in HCT116 Colorectal Cancer Cells

c-Jun N-terminal kinase (JNK) is activated by chemotherapeutic reagents including natural plant polyphenols, and cell fate is determined by activated phospho-JNK as survival or death depending on stimuli and cell types. The purpose of this study was to elucidate the role of JNK on the anticancer eff...

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Bibliographic Details
Main Authors: Eun Joo Jung, Anjugam Paramanantham, Hye Jung Kim, Sung Chul Shin, Gon Sup Kim, Jin-Myung Jung, Chung Ho Ryu, Soon Chan Hong, Ky Hyun Chung, Choong Won Kim, Won Sup Lee
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Artemisia annua</i> L.
polyphenols
cell death
ROS
JNK
colorectal cancer
Online Access:https://www.mdpi.com/1422-0067/22/3/1366

Internet

https://www.mdpi.com/1422-0067/22/3/1366

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