Effect of a Fourth Dose of mRNA Vaccine and of Immunosuppression in Preventing SARS-CoV-2 Breakthrough Infections in Heart Transplant Patients

Effect of a Fourth Dose of mRNA Vaccine and of Immunosuppression in Preventing SARS-CoV-2 Breakthrough Infections in Heart Transplant Patients

Patients with heart transplantation (HT) have an increased risk of COVID-19 disease and the efficacy of vaccines on antibody induction is lower, even after three or four doses. The aim of our study was to assess the efficacy of four doses on infections and their interplay with immunosuppression. We...

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Bibliographic Details
Main Authors: Marco Masetti, Maria Francesca Scuppa, Alessio Aloisio, Laura Giovannini, Laura Borgese, Stefania Manno, Beatrice Tazza, Renato Pascale, Cecilia Bonazzetti, Natascia Caroccia, Mario Sabatino, Giosafat Spitaleri, Pierluigi Viale, Maddalena Giannella, Luciano Potena
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Microorganisms
Subjects:
COVID-19
heart transplantation
mRNA vaccines
fourth dose
immunosuppression
breakthrough infections
Online Access:https://www.mdpi.com/2076-2607/11/3/755

Internet

https://www.mdpi.com/2076-2607/11/3/755

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