Efficient, cell-based simulations of cardiac electrophysiology; The Kirchhoff Network Model (KNM)

Abstract Mathematical models based on homogenized representation of cardiac tissue have greatly improved our understanding of cardiac electrophysiology. However, these models are too coarse to investigate the dynamics at the level of the myocytes since the cells are not present in homogenized models...

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Bibliographic Details
Main Authors: Karoline Horgmo Jæger, Aslak Tveito
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-023-00288-3