Quantification of hematopoietic stem and progenitor cells by targeted DNA methylation analysis

Quantification of hematopoietic stem and progenitor cells by targeted DNA methylation analysis

Abstract Hematopoietic stem and progenitor cells (HSPCs) are quantified in daily clinical practice by flow cytometry. In this study, we provide proof of concept that HSPCs can also be estimated by targeted DNA methylation (DNAm) analysis. The DNAm levels at three individual CG dinucleotides (CpG sit...

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Chi tiết về thư mục
Những tác giả chính: Ledio Bocova, Wouter Hubens, Cordula Engel, Steffen Koschmieder, Edgar Jost, Wolfgang Wagner
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: BMC 2023-06-01
Loạt:Clinical Epigenetics
Những chủ đề:
DNA methylation
Biomarker
Epigenetic
Hematopoietic stem cells
HSC
CD34
Truy cập trực tuyến:https://doi.org/10.1186/s13148-023-01521-w

Internet

https://doi.org/10.1186/s13148-023-01521-w

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