Quantification of hematopoietic stem and progenitor cells by targeted DNA methylation analysis

Abstract Hematopoietic stem and progenitor cells (HSPCs) are quantified in daily clinical practice by flow cytometry. In this study, we provide proof of concept that HSPCs can also be estimated by targeted DNA methylation (DNAm) analysis. The DNAm levels at three individual CG dinucleotides (CpG sit...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Ledio Bocova, Wouter Hubens, Cordula Engel, Steffen Koschmieder, Edgar Jost, Wolfgang Wagner
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: BMC 2023-06-01
Цуврал:Clinical Epigenetics
Нөхцлүүд:
Онлайн хандалт:https://doi.org/10.1186/s13148-023-01521-w