Nanoplateletsomes restrain metastatic tumor formation through decoy and active targeting in a preclinical mouse model

Nanoplateletsomes restrain metastatic tumor formation through decoy and active targeting in a preclinical mouse model

Platelets buoy up cancer metastasis via arresting cancer cells, enhancing their adhesion, and facilitating their extravasation through the vasculature. When deprived of intracellular and granular contents, platelet decoys could prevent metastatic tumor formation. Inspired by these, we developed nano...

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Bibliographic Details
Main Authors: Longlong Zhang, Yuefei Zhu, Xunbin Wei, Xing Chen, Yang Li, Ying Zhu, Jiaxuan Xia, Yiheng Huang, Yongzhuo Huang, Jianxin Wang, Zhiqing Pang
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Nanoplateletsome
Breast cancer
Tumor metastasis
Circulating tumor cells
Nanodecoy
Immunosuppressive micrometastatic environment
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383522000181

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http://www.sciencedirect.com/science/article/pii/S2211383522000181

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