Contrasting effects of leptin on food anticipatory and total locomotor activity.

Obese, leptin deficient obob mice have profoundly decreased activity and increased food seeking behavior. The decreased activity has been attributed to obesity. In mice, we tested the hypothesis that leptin increases total locomotor activity but inhibits food anticipatory activity. We also sought to...

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Bibliographic Details
Main Authors: Ana C Ribeiro, Giovanni Ceccarini, Christophe Dupré, Jeffrey M Friedman, Donald W Pfaff, Allyn L Mark
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3154408?pdf=render