A Method for Using Cell-Penetrating Peptides for Loading Plasmid DNA into Secreted Extracellular Vesicles
The low bioavailability and high toxicity of plasmid DNA (pDNA)-based therapeutics pose challenges for their in vivo application. Extracellular vesicles (EVs) have great potential to overcome these limitations, as they are biocompatible native cargo carriers. Various methods for loading pDNA into EV...
主要な著者: | , , , , , , , |
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フォーマット: | 論文 |
言語: | English |
出版事項: |
MDPI AG
2023-12-01
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シリーズ: | Biomolecules |
主題: | |
オンライン・アクセス: | https://www.mdpi.com/2218-273X/13/12/1751 |