A Method for Using Cell-Penetrating Peptides for Loading Plasmid DNA into Secreted Extracellular Vesicles

The low bioavailability and high toxicity of plasmid DNA (pDNA)-based therapeutics pose challenges for their in vivo application. Extracellular vesicles (EVs) have great potential to overcome these limitations, as they are biocompatible native cargo carriers. Various methods for loading pDNA into EV...

詳細記述

書誌詳細
主要な著者: Jekaterina Nebogatova, Heleri Heike Härk, Anett Puskar, Ly Porosk, Paolo Guazzi, Moataz Dowaidar, Ülo Langel, Kaido Kurrikoff
フォーマット: 論文
言語:English
出版事項: MDPI AG 2023-12-01
シリーズ:Biomolecules
主題:
オンライン・アクセス:https://www.mdpi.com/2218-273X/13/12/1751