Methylparaben induces hepatic glycolipid metabolism disorder by activating the IRE1α-XBP1 signaling pathway in male mice

Methylparaben induces hepatic glycolipid metabolism disorder by activating the IRE1α-XBP1 signaling pathway in male mice

Methylparaben (MP), a preservative widely used in daily supplies, exists in both the environment and the human body. However, the potential health risks posed by MP remain unclear. This study aimed to unravel the mechanisms by which MP disrupts glucose and lipid homeostasis. For this, we administere...

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Bibliographic Details
Main Authors: Haining Du, Jiaxin Li, Xiangjuan Wei, Daqian Yang, Boya Zhang, Xingpei Fan, Meimei Zhao, Ruijiao Zhu, Ziyi Zhang, Yuxia Zhang, Xiaoyan Li, Ning Gu
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Environment International
Subjects:
MP
ER stress
XBP1
Inflammation
Insulin resistance
Lipid metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S016041202400031X

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http://www.sciencedirect.com/science/article/pii/S016041202400031X

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