Structurally Mapping Antibody Repertoires

Structurally Mapping Antibody Repertoires

Every human possesses millions of distinct antibodies. It is now possible to analyze this diversity via next-generation sequencing of immunoglobulin genes (Ig-seq). This technique produces large volume sequence snapshots of B-cell receptors that are indicative of the antibody repertoire. In this pap...

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Bibliographic Details
Main Authors: Konrad Krawczyk, Sebastian Kelm, Aleksandr Kovaltsuk, Jacob D. Galson, Dominic Kelly, Johannes Trück, Cristian Regep, Jinwoo Leem, Wing K. Wong, Jaroslaw Nowak, James Snowden, Michael Wright, Laura Starkie, Anthony Scott-Tucker, Jiye Shi, Charlotte M. Deane
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
antibody specificity
B-cell receptor
next-generation sequencing
structural homology
protein
bioinformatics tools
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01698/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01698/full

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