Tb1, a Neurotoxin from <i>Tityus bahiensis</i> Scorpion Venom, Induces Epileptic Seizures by Increasing Glutamate Release

Tb1, a Neurotoxin from <i>Tityus bahiensis</i> Scorpion Venom, Induces Epileptic Seizures by Increasing Glutamate Release

Here, we report the neurotoxic effects aroused by the intracerebral injection (in rats) of Tb1, which is a neurotoxin isolated from <i>Tityus bahiensis</i> scorpion venom. Biochemical analyses have demonstrated that this toxin is similar to the gamma toxin from <i>T. serrulatus<...

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Bibliographic Details
Main Authors: Emidio Beraldo Neto, Lucas Alves de Freitas, Daniel Carvalho Pimenta, Ivo Lebrun, Ana L. A. Nencioni
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Toxins
Subjects:
scorpion toxins
hippocampus
seizures
neurotransmitters
neuronal damage
epilepsy
Online Access:https://www.mdpi.com/2072-6651/12/2/65

Internet

https://www.mdpi.com/2072-6651/12/2/65

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