Targeting Glucose Transporters for Breast Cancer Therapy: The Effect of Natural and Synthetic Compounds

Reprogramming of cellular energy metabolism is widely accepted to be a cancer hallmark. The deviant energetic metabolism of cancer cells-known as the Warburg effect-consists in much higher rates of glucose uptake and glycolytic oxidation coupled with the production of lactic acid, even in the presen...

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Bibliographic Details
Main Authors: Ana M. Barbosa, Fátima Martel
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/1/154