The JNK pathway is a key mediator of Anopheles gambiae antiplasmodial immunity.

The innate immune system of Anopheles gambiae mosquitoes limits Plasmodium infection through multiple molecular mechanisms. For example, midgut invasion by the parasite triggers an epithelial nitration response that promotes activation of the complement-like system. We found that suppression of the...

Full description

Bibliographic Details
Main Authors: Lindsey S Garver, Giselle de Almeida Oliveira, Carolina Barillas-Mury
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3764222?pdf=render