Chlorogenic Acid Protects against Advanced Alcoholic Steatohepatitis in Rats via Modulation of Redox Homeostasis, Inflammation, and Lipogenesis

Chlorogenic Acid Protects against Advanced Alcoholic Steatohepatitis in Rats via Modulation of Redox Homeostasis, Inflammation, and Lipogenesis

The aim of this study was to evaluate the therapeutic effects of chlorogenic acid (CGA) in rats with advanced alcoholic steatohepatitis. The rats were fed on a high-fat diet and gavaged with ethanol (4 g/kg) for 8 weeks. The livers of ethanol-treated rats showed steatosis; necrosis and mononuclear i...

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Bibliographic Details
Main Authors: Vyacheslav Buko, Ilya Zavodnik, Grażyna Budryn, Małgorzata Zakłos-Szyda, Elena Belonovskaya, Siarhei Kirko, Dorota Żyżelewicz, Agnieszka Zakrzeska, Aliaksei Bakunovich, Viktor Rusin, Valentina Moroz
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Nutrients
Subjects:
in vivo study
alcoholic steatohepatitis
oxidative stress
inflammatory response
chlorogenic acid
Online Access:https://www.mdpi.com/2072-6643/13/11/4155

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https://www.mdpi.com/2072-6643/13/11/4155

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