Mechanical coupling coordinates microtubule growth

During mitosis, kinetochore-attached microtubules form bundles (k-fibers) in which many filaments grow and shorten in near-perfect unison to align and segregate each chromosome. However, individual microtubules grow at intrinsically variable rates, which must be tightly regulated for a k-fiber to be...

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Bibliographic Details
Main Authors: Bonnibelle K Leeds, Katelyn F Kostello, Yuna Y Liu, Christian R Nelson, Sue Biggins, Charles L Asbury
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/89467