MTBP enhances the activation of transcription factor ETS-1 and promotes the proliferation of hepatocellular carcinoma cells

MTBP enhances the activation of transcription factor ETS-1 and promotes the proliferation of hepatocellular carcinoma cells

Increasing evidence indicates that the oncoprotein murine double minute (MDM2) binding protein (MTBP) can be considered a pro-oncogene of human malignancies; however, its function and mechanisms in hepatocellular carcinoma (HCC) are still not clear. In the present work, our results demonstrate that...

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Bibliographic Details
Main Authors: Hongbo Wang, Fang Chu, Li Zhijie, Qian Bi, Li Lixin, Yunlong Zhuang, Zhang Xiaofeng, Xiaofeng Niu, Dali Zhang, He Xi, Bo-an Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
Hepatocellular carcinoma
MDM2 binding protein
E26 transformation specific sequence 1
proliferation
transcription factor activation
protein interaction
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.985082/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.985082/full

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