Dual mechanism of ion permeation through VDAC revealed with inorganic phosphate ions and phosphate metabolites.

In the exchange of metabolites and ions between the mitochondrion and the cytosol, the voltage-dependent anion channel (VDAC) is a key element, as it forms the major transport pathway for these compounds through the mitochondrial outer membrane. Numerous experimental studies have promoted the idea t...

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Bibliographic Details
Main Authors: Eva-Maria Krammer, Giang Thi Vu, Fabrice Homblé, Martine Prévost
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4393092?pdf=render