Plasmacytoid Dendritic Cells in the Tumor Microenvironment: Immune Targets for Glioma Therapeutics

Plasmacytoid Dendritic Cells in the Tumor Microenvironment: Immune Targets for Glioma Therapeutics

Adenovirus-mediated delivery of the immune-stimulatory cytokine Flt3L and the conditionally cytotoxic thymidine kinase (TK) induces tumor regression and long-term survival in preclinical glioma (glioblastoma multiforme [GBM]) models. Flt3L induces expansion and recruitment of plasmacytoid dendritic...

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Main Authors: Marianela Candolfi, Gwendalyn D. King, Kader Yagiz, James F. Curtin, Yohei Mineharu, AKM Ghulam Muhammad, David Foulad, Kurt M. Kroeger, Nick Barnett, Regis Josien, Pedro R. Lowenstein, Maria G. Castro
Format: Article
Language:English
Published: Elsevier 2012-08-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558612800091

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http://www.sciencedirect.com/science/article/pii/S1476558612800091

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