Ovulatory signal-triggered chromatin remodeling in ovarian granulosa cells by HDAC2 phosphorylation activation-mediated histone deacetylation

Ovulatory signal-triggered chromatin remodeling in ovarian granulosa cells by HDAC2 phosphorylation activation-mediated histone deacetylation

Abstract Background Epigenetic reprogramming is involved in luteinizing hormone (LH)-induced ovulation; however, the underlying mechanisms are largely unknown. Results We here observed a rapid histone deacetylation process between two waves of active transcription mediated by the follicle-stimulatin...

Full description

Bibliographic Details
Main Authors: Jiamin Jin, Peipei Ren, Xiang Li, Yinyi Zhang, Weijie Yang, Yerong Ma, Mengru Lai, Chao Yu, Songying Zhang, Yin-Li Zhang
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Epigenetics & Chromatin
Subjects:
Luteinizing hormone
Granulosa cells
HDAC2
H3K27Ac
Ovulation
Chromatin remodeling
Online Access:https://doi.org/10.1186/s13072-023-00485-8

Internet

https://doi.org/10.1186/s13072-023-00485-8

Similar Items