The emerging roles of Shank3 in cardiac function and dysfunction

Shank3 is a member of the Shank family proteins (Shank1–3), which are abundantly present in the postsynaptic density (PSD) of neuronal excitatory synapses. As a core scaffold in the PSD, Shank3 plays a critical role in organizing the macromolecular complex, ensuring proper synaptic development and f...

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Bibliographic Details
Main Authors: Yoonhee Kim, Tae Hee Ko, Chunmei Jin, Yinhua Zhang, Hyae Rim Kang, Ruiying Ma, Huiling Li, Jong-Il Choi, Kihoon Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1191369/full