Inhibition of <i>TP53</i> Mutant Oral Cancer by Reactivating p53

Inhibition of <i>TP53</i> Mutant Oral Cancer by Reactivating p53

Background: Mutation of p53 is a frequent event, and mutant p53 exhibits low levels of acetylation and phosphorylation. This study aimed to investigate the effect of the histone deacetylase (HDAC) inhibitor, 4-hexylresorcinol (4HR), on the acetylation and phosphorylation of mutant p53 carcinoma cell...

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Bibliographic Details
Main Authors: Yei-Jin Kang, Dae-Won Kim, Xiangguo Che, Je-Yong Choi, Seong-Gon Kim
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Applied Sciences
Subjects:
4-hexylresorcinol
p53
phosphorylation
acetylation
Online Access:https://www.mdpi.com/2076-3417/12/12/5921

Internet

https://www.mdpi.com/2076-3417/12/12/5921

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