Weight-adjusted dosing of fibrinogen concentrate and cryoprecipitate in the treatment of hypofibrinogenaemic bleeding adult cardiac surgical patients: a post hoc analysis of the Fibrinogen Replenishment in cardiac surgery randomised controlled trial

Weight-adjusted dosing of fibrinogen concentrate and cryoprecipitate in the treatment of hypofibrinogenaemic bleeding adult cardiac surgical patients: a post hoc analysis of the Fibrinogen Replenishment in cardiac surgery randomised controlled trial

Background: Hypofibrinogenaemia is associated with excessive bleeding after cardiac surgery. Our aim was to compare the efficacy and safety of weight-adjusted vs empiric dosing of fibrinogen replacement in cardiac surgery. Methods: In the Fibrinogen Replenishment in Cardiac Surgery (FIBRES) RCT, pat...

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Bibliographic Details
Main Authors: Cian Devine, Justyna Bartoszko, Jeannie Callum, Keyvan Karkouti
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:BJA Open
Subjects:
cardiac surgery
coagulopathy
fibrinogen
haemostasis
transfusion
Online Access:http://www.sciencedirect.com/science/article/pii/S2772609622000156

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http://www.sciencedirect.com/science/article/pii/S2772609622000156

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