In silico prioritisation of microRNA-associated common variants in multiple sclerosis

In silico prioritisation of microRNA-associated common variants in multiple sclerosis

Abstract Background Genome-wide association studies (GWAS) have highlighted over 200 autosomal variants associated with multiple sclerosis (MS). However, variants in non-coding regions such as those encoding microRNAs have not been explored thoroughly, despite strong evidence of microRNA dysregulati...

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Bibliographic Details
Main Authors: Ifeolutembi A. Fashina, Claire E. McCoy, Simon J. Furney
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Human Genomics
Subjects:
Non-coding RNA
microRNA
3′UTR binding sites
GWAS
microRNA–target prediction
Seed
Online Access:https://doi.org/10.1186/s40246-023-00478-4

Internet

https://doi.org/10.1186/s40246-023-00478-4

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