Hypoxia-responsive circular RNA circAAGAB reduces breast cancer malignancy by activating p38 MAPK and sponging miR-378 h

Hypoxia-responsive circular RNA circAAGAB reduces breast cancer malignancy by activating p38 MAPK and sponging miR-378 h

Abstract Background Breast cancer is a prevalent disease in women, with high prevalence worldwide. The hypoxic microenvironment of solid tumors develops during the progress of carcinogenesis and leads to greater malignancy and treatment resistance. Recently, accumulating evidence indicates that non-...

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Bibliographic Details
Main Authors: Kuan-Yi Lee, Chia-Ming Liu, Li-Han Chen, Chien-Yueh Lee, Tzu-Pin Lu, Li-Ling Chuang, Liang-Chuan Lai
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Cancer Cell International
Subjects:
circAAGAB
Hypoxia
Breast cancer
Tumor suppressor
p38 MAPK
miRNA sponge
Online Access:https://doi.org/10.1186/s12935-023-02891-0

Internet

https://doi.org/10.1186/s12935-023-02891-0

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