Vertical sleeve gastrectomy reduces blood pressure and hypothalamic endoplasmic reticulum stress in mice

Vertical sleeve gastrectomy reduces blood pressure and hypothalamic endoplasmic reticulum stress in mice

Bariatric surgery, such as vertical sleeve gastrectomy (VSG), causes remarkable improvements in cardiometabolic health, including hypertension remission. However, the mechanisms responsible remain undefined and poorly studied. Therefore, we developed and validated the first murine model of VSG that...

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Bibliographic Details
Main Authors: Anne K. McGavigan, Zachariah M. Henseler, Darline Garibay, Scott D. Butler, Sisitha Jayasinghe, Ruth E. Ley, Robin L. Davisson, Bethany P. Cummings
Format: Article
Language:English
Published: The Company of Biologists 2017-03-01
Series:Disease Models & Mechanisms
Subjects:
Vertical sleeve gastrectomy
Hypertension
ER stress
Mouse model
Online Access:http://dmm.biologists.org/content/10/3/235

Internet

http://dmm.biologists.org/content/10/3/235

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