LM-DTI: a tool of predicting drug-target interactions using the node2vec and network path score methods

Introduction: Drug-target interaction (DTI) prediction is a key step in drug function discovery and repositioning. The emergence of large-scale heterogeneous biological networks provides an opportunity to identify drug-related target genes, which led to the development of several computational metho...

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Bibliographic Details
Main Authors: Jianwei Li, Yinfei Wang, Zhiguang Li, Hongxin Lin, Baoqin Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1181592/full