Protective effects of Boswellia and Curcuma extract on oxaliplatin-induced neuropathy via modulation of NF-κB signaling

Protective effects of Boswellia and Curcuma extract on oxaliplatin-induced neuropathy via modulation of NF-κB signaling

Oxaliplatin is a third-generation anticancer agent with better efficacy, lower toxicity, and a broad spectrum of antineoplastic activity. Its use is frequently associated with chronic oxaliplatin-induced neuropathy (OIN), a cumulative phenomenon manifesting as loss of sensation, paresthesia, dysesth...

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Bibliographic Details
Main Authors: Sakshi Mahajan, Varun Sureja, Dharmeshkumar Kheni, Vishal Dubey, Kiran Bhupathiraju, Venkata KrishnaRaju Alluri, Anuradha Majumdar
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Toxicology Reports
Subjects:
Oxaliplatin
Neuropathy
NF-κB, Inflammation
Oxidative stress
Curcumin, Boswellia
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750024001641

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http://www.sciencedirect.com/science/article/pii/S2214750024001641

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