LRIG3 Suppresses Angiogenesis by Regulating the PI3K/AKT/VEGFA Signaling Pathway in Glioma

LRIG3 Suppresses Angiogenesis by Regulating the PI3K/AKT/VEGFA Signaling Pathway in Glioma

High levels of microvessel density (MVD) indicate poor prognosis in patients with malignant glioma. Leucine-rich repeats and immunoglobulin-like domains (LRIG) 3, a potential tumor suppressor, plays an important role in tumor progression and may serve as a biomarker in many human cancers. However, i...

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Bibliographic Details
Main Authors: Chenghao Peng, Hanmin Chen, Youwei Li, Hang Yang, Peizhong Qin, Baojun Ma, Qiuhong Duan, Baofeng Wang, Feng Mao, Dongsheng Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
glioma
angiogenesis
LRIG3
vascular endothelial growth factor A
PI3K/AKT
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.621154/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.621154/full

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