Clinical significance of the expression of FOXP3 and TIGIT in Merkel cell carcinoma

Clinical significance of the expression of FOXP3 and TIGIT in Merkel cell carcinoma

Abstract The pathogenesis of 80% of Merkel cell carcinoma (MCC) cases is associated with Merkel cell polyomavirus (MCPyV). Forkhead helix transcription factor P3 (FOXP3) and the T cell immunoreceptor with immunoglobulin and immunoreceptor tyrosine-based inhibition motif domains (TIGIT)–CD155 pathway...

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Bibliographic Details
Main Authors: Takeshi Iwasaki, Kazuhiko Hayashi, Michiko Matsushita, Daisuke Nonaka, Takamasa Matsumoto, Midori Taniguchi, Satoshi Kuwamoto, Yoshihisa Umekita, Yoshinao Oda
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-40050-7

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https://doi.org/10.1038/s41598-023-40050-7

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