Homotopic contralesional excitation suppresses spontaneous circuit repair and global network reconnections following ischemic stroke

Homotopic contralesional excitation suppresses spontaneous circuit repair and global network reconnections following ischemic stroke

Understanding circuit-level manipulations that affect the brain’s capacity for plasticity will inform the design of targeted interventions that enhance recovery after stroke. Following stroke, increased contralesional activity (e.g. use of the unaffected limb) can negatively influence recovery, but...

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Bibliographic Details
Main Authors: Annie R Bice, Qingli Xiao, Justin Kong, Ping Yan, Zachary Pollack Rosenthal, Andrew W Kraft, Karen P Smith, Tadeusz Wieloch, Jin-Moo Lee, Joseph P Culver, Adam Q Bauer
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-06-01
Series:eLife
Subjects:
stroke recovery
functional connectivity
plasticity
optical intrinsic signal imaging
functional neuroimaging
optogenetics
Online Access:https://elifesciences.org/articles/68852

Internet

https://elifesciences.org/articles/68852

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