Analysis of the lncRNA–miRNA–mRNA Network Reveals a Potential Regulatory Mechanism of EGFR-TKI Resistance in NSCLC

Analysis of the lncRNA–miRNA–mRNA Network Reveals a Potential Regulatory Mechanism of EGFR-TKI Resistance in NSCLC

Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are widely used for patients with EGFR-mutated lung cancer. Despite its initial therapeutic efficacy, most patients eventually develop drug resistance, which leads to a poor prognosis in lung cancer patients. Previous investigat...

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Bibliographic Details
Main Authors: Dandan Ding, Jufeng Zhang, Zhiming Luo, Huazhen Wu, Zexiao Lin, Weicheng Liang, Xingyang Xue
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Genetics
Subjects:
EGFR-TKIs
drug resistance
long non-coding RNA
LINC01128
lung cancer-diagnosis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.851391/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.851391/full

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