The role of late-differentiated T cells, a proxy for IFN-γ-production, in older adults’ social networks

Interferon-γ (IFN-γ), an inflammatory biomarker that promotes antiviral immunity, may be a prerequisite for sociability. IFN-γ production in older adulthood is driven by late-differentiated CD8+ T cells, particularly CD28−and CD57+ subsets, which increase with age, reduce immune response, and increa...

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Bibliographic Details
Main Authors: Elana M. Gloger, Stephanie T. Judge, Rebecca G. Reed, Steven R. Presnell, Ahmad Al-Attar, Charles T. Lutz, Suzanne C. Segerstrom
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Brain, Behavior, & Immunity - Health
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354622001028