Controversial causal association between IGF family members and osteoporosis: a Mendelian randomization study between UK and FinnGen biobanks

Controversial causal association between IGF family members and osteoporosis: a Mendelian randomization study between UK and FinnGen biobanks

ObjectivesOsteoporosis, a prevalent skeletal disorder characterized by reduced bone strength, is closely linked to the IGF system, crucial for skeletal metabolism. However, the precise nature of this relationship remains elusive. In this study, we employed Mendelian randomization (MR) to unravel the...

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Bibliographic Details
Main Authors: Jie Tang, Chanjuan Zhao, Sha Lin, Xing Li, Binlu Zhu, Yifei Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Endocrinology
Subjects:
osteoporosis
IGF-1
IGF family
developmental disorders
Mendelian randomization
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1332803/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1332803/full

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