Profiling of G protein-coupled receptors in vagal afferents reveals novel gut-to-brain sensing mechanisms

Profiling of G protein-coupled receptors in vagal afferents reveals novel gut-to-brain sensing mechanisms

Objectives: G protein-coupled receptors (GPCRs) act as transmembrane molecular sensors of neurotransmitters, hormones, nutrients, and metabolites. Because unmyelinated vagal afferents richly innervate the gastrointestinal mucosa, gut-derived molecules may directly modulate the activity of vagal affe...

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Bibliographic Details
Main Authors: Kristoffer L. Egerod, Natalia Petersen, Pascal N. Timshel, Jens C. Rekling, Yibing Wang, Qinghua Liu, Thue W. Schwartz, Laurent Gautron
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877818302023

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http://www.sciencedirect.com/science/article/pii/S2212877818302023

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