Significant Roles of Notch <i>O</i>-Glycosylation in Cancer

Notch signaling, which was initially identified in <i>Drosophila</i> wing morphogenesis, plays pivotal roles in cell development and differentiation. Optimal Notch pathway activity is essential for normal development and dysregulation of Notch signaling leads to various human diseases, i...

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Bibliographic Details
Main Authors: Weiwei Wang, Tetsuya Okajima, Hideyuki Takeuchi
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/6/1783