Specific Non-Reducing Ends in Heparins from Different Animal Origins: Building Blocks Analysis Using Reductive Amination Tagging by Sulfanilic Acid
Heparins are linear sulfated polysaccharides widely used as anticoagulant drugs. Their nonreducing-end (NRE) has been little investigated due to challenges in their characterization, but is known to be partly generated by enzymatic cleavage with heparanases, resulting in <i>N</i>-sulfate...
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Format: | Article |
Language: | English |
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MDPI AG
2020-11-01
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Series: | Molecules |
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Online Access: | https://www.mdpi.com/1420-3049/25/23/5553 |